Youyang Zhao
Professor
University of Illinois
USA
Biography
He is a Professor in pharmacology department of Uiversity of Illinois, Chicago
Research Interest
Recovery of endothelial barrier integrity after vascular injury is vital for endothelial barrier function and vascular homeostasis. Endothelial dysfunction plays a critical role in the initiation and progression of vascular diseases such as acute lung injury/acute respiratory distress syndrome, and atherosclerosis. A part of the research in the lab is to elucidate the molecular mechanisms of endothelial regeneration and restoration of endothelial barrier integrity following inflammatory lung vascular injury, understand the mechanisms of action of stem/endothelial progenitor cells-mediated endothelial regeneration, vascular repair, and neovascularization using the unique mouse model with endothelial cell-restricted deletion of FoxM1 (JCI, 116:2333-43, 2006; JEM, 207:1675-85, 2010) and other genetically modified animal models