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Tissue Science 2018

About Conference


The 12th International conference  on Tissue Engineering and Regenerative Medicine which is going to be held during November 9-10 2018 at Atlanta, Georgia, USA  will  bring together world-class personalities working on stem cells, tissue engineering and  regenerative medicine to discuss materials-related strategies for disease remediation and tissue repair. Bone tissue engineeringsoft tissuestissue imagingtissue implant, cartilage and skin defects are a special focus along with applying basic science and engineering principles from diverse areas towards solving clinically relevant genetical problems.

We welcome you to Tissue Science Conference, to be held on November 9-10 2018 at Atlanta, Georgia, USA. This conference presents information regarding cutting-edge developments in all areas of tissue engineering, stem cell research, regenerative medicine research including the biology, medicine, applications and regulations of stem cells. Topics of discussion include recent developments in pre-clinical and clinical trials of stem cell therapy, regenerative medicine and tissue engineering, cancer stem cells, immunotherapy, stem cell reprogramming, and regulatory policies regarding stem cell research.

After the success of the 6th international Conference  on Tissue Engineering and Regenerative Medicine  in 2017, it’s time for the tissue engineering and regenerative medicine industries to come together and looking forward for  the  next 10 years of commercial successes within these two sectors.

The World Conference on Regenerative Medicine  has traditionally focused on developing the commercial aspects of  tissue science research  with the addition of innovation within stem cellsregenerative medicine, notably tissue engineering.

Now the first regenerative medicine therapies have made it to market, it is important, for the success of the sector, to move forward and include new projects and innovations that are coming out of academia and university spin-outs. These will be both new developments in regenerative medicine research but also within the use of tissue engineering and stem cells for drug discovery.

Alongside the stem cells content, there is an increasing amount of demand for other forms of regenerative medicine and so the Tissue Science conference will move to include more commercial opportunities within the field of tissue engineering: markedly biological scaffolds, 3D bio printing and organ regeneration.

Through the last 5 years the Tissue Science Conference has built up a reputation for delivering high-level commercial content and bringing together the senior executives and thought-leaders within the space.

Sessions And Tracks

1. Tissue Science & Engineering

Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physicochemical factors to improve or replace biological tissues. Tissue engineering involves the use of a scaffold for the formation of new viable tissue for a medical purpose. While it was once categorized as a sub-field of biomaterials, having grown in scope and importance it can be considered as a field in its own. While most definitions of tissue engineering cover a broad range of applications, in practice the term is closely associated with applications that repair or replace portions of or whole tissues (i.e., bone, cartilage, blood vessels, bladder, skin, muscle etc.). Often, the tissues involved require certain mechanical and structural properties for proper functioning. The term has also been applied to efforts to perform specific biochemical functions using cells within an artificially-created support system (e.g. an artificial pancreas, or a bio artificial liver). The term regenerative medicine is often used synonymously with tissue engineering, although those involved in regenerative medicine place more emphasis on the use of stem cells or progenitor cells to produce tissues.

Related Conferences

Drug delivery and tissue engineering conference 2018, February 4-8, 2018, Singapore; 20th International conference on Tissue engineering and Biomaterials, Feb 19-20, 2018, Paris; Global Summit on Stem Cell & Tissue Engineering 2018, July 23-24, 2018 Barcelona, Spain.19th International Conference on Tissue Engineering and RegenerativeMedicine Applications, September21-22, Paris, France;12th International conference on Tissue Engineering and Regenerative Medicine, November 09-10, Atlanta;3rd world Congress on Human Genetics & Genetic Disorders, October 20-21,2017,Canada; 12th International conference on Tissue Preservation & Biobanking, November 09-10, Atlanta;7th Annual Congress & Medical Expo on Primary Health Care and Nursing 2018,June 25-26,Canada.

2. Regenerative Medicine

Regenerative medicine is the branch of medicine that develops methods to regrow, repair or replace damaged or diseased cells, organs or tissues. Regenerative medicine includes the generation and use of therapeutic stem cells, tissue engineering and the production of artificial organs. Regenerative medicine seeks to replace tissue or organs that have been damaged by disease, trauma, or congenital issues, vs. the current clinical strategy that focuses primarily on treating the symptoms. The tools used to realize these outcomes are tissue engineering, cellular therapies, and medical devices and artificial organs.

3. Bio fabrication & 3 D-Bio printing in Life Sciences

The fields of TissueEngineering and 3D-Bioprinting are important for ultimately realizing the full potential of regenerative medicine.  The potential to "3D-print" tissues and organs is gaining extensive interest and this conference brings together the academic as well as industry stakeholders in these expanding fields.
From a technology/methodology perspective, this conference addresses Tissue Engineering as well as Bio fabrication and Bio printing as we explore the latest developments in this field.  Indeed, the field of Synthetic Biology currently with many ramifications and application areas is an important component of the broader Bio fabrication space and therefore an entire conference track is devoted to this expanding field. There will be a session focusing on the Clinical Translation of Tissue Engineering as means to provide a Current State of the Landscape and Trajectory for the Future. Posters from delegates are welcomed as a means to disseminate the most up-to-date research and commercial applications which complement the presentations from the leaders in these fields. A co-located exhibition brings forth the technologies and commercial products in the Tissue Engineering, 3D-Bioprinting and Bio fabrication fields and features companies large and small.

4. Tissue Regeneration using Nanotechnology

The recent integration of emerging nanotechnology into biology and biomedicine has resulted in a range of innovative Nano engineering efforts for the repair and regeneration of tissues and organs. Thus, it is expected that Nano engineering approaches to biomedical applications can contribute to addressing the present issue of personal and global health care and its economic burden for more than 7 billion people. Biomimetic Nano patterns alone can direct the differentiation of stem cells without involvement of exogenous soluble biochemical factors. This regulation of cellular behaviour by nanotechnology is one of many examples demonstrating the significant applications of Nano engineering in biomedicine. This special issue includes four review papers and seven research articles that provide an insight into current Nano engineering approaches to the repair or regeneration of tissues and organs.

5. Tooth Regeneration

Tooth regeneration is a stem cell based regenerative medicine procedure in the field of tissue engineering and stem cell biology to replace damaged or lost teeth by regrowing them from autologous stem cells.

As a source of the new bioengineered teeth somatic stem cells are collected and reprogrammed to induced pluripotent stem cells which can be placed in the dental lamina directly or placed in a reabsorbable biopolymer in the shape of the new tooth.

Related Conferences

Drug delivery and tissue engineering conference 2018, February 4-8, 2018, Singapore; 20th International conference on Tissue engineering and Biomaterials, Feb 19-20, 2018, Paris; Global Summit on Stem Cell & Tissue Engineering 2018, July 23-24, 2018 Barcelona, Spain.19th International Conference on Tissue Engineering and RegenerativeMedicine Applications, September21-22, Paris, France;12th International conference on Tissue Engineering and Regenerative Medicine, November 09-10, Atlanta;3rd world Congress on Human Genetics & Genetic Disorders, October 20-21,2017,Canada; 12th International conference on Tissue Preservation & Biobanking, November 09-10, Atlanta;7th Annual Congress & Medical Expo on Primary Health Care and Nursing 2018,June 25-26,Canada.

6. Advances in Stem Cell

Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell. Stem cells are distinguished from other cell types by two important characteristics. First, they are unspecialized cells capable of renewing themselves through cell division, sometimes after long periods of inactivity. Second, under certain physiologic or experimental conditions, they can be induced to become tissue or organ-specific cells with special functions. In some organs, such as the gut and bone marrow, stem cells regularly divide to repair and replace worn out or damaged tissues. In other organs, however, such as the pancreas and the heart, stem cells only divide under special conditions.

7. Biomedical engineering techniques

Biomedical engineering is the application of engineering principles in designing techniques and technology to medicine and biology for healthcare purposes. This field link the gap between engineering and medicine, combining the design and problem solving skills of engineering with medical and biological sciences to advance health care treatment, including diagnosis, monitoring, and therapeutics. The field transitions from being an interdisciplinary specialization among already-established fields enhance the impact of health care. Biomedical techniques on tissue science and regenerative medicine are computer modelling, Tissue Mechanics, Bio patterning technology, Bio-inspired Computing to promote tissue regeneration.

8. Tissue Repair & Regeneration

Tissue repair and regeneration following injury or disease are often thought to recapitulate embryonic development by using similar molecular and cellular pathways. In addition, many embryonic tissues, such as the spinal cord, heart, and limbs, have some regenerative potential and may utilize mechanisms that can be exogenously activated in adult tissues. For example, BMP signalling regulates nervous system development, and SMAD reactivation plays a critical role in adult nerve regeneration and repair in animal models of spinal cord injury. While similar molecular pathways are utilized during embryogenesis and adult tissue regeneration, recent reports suggest the mechanisms by which these developmental programs are reactivated and maintained may vary in adult tissues. Adult fish and amphibians have a remarkable capacity for tissue regeneration, while mammals have a limited regenerative capacity.

9. Biological Tissue Substitutes

Bioengineered skin and soft tissue substitutes may be derived from human tissue (autologous or allogeneic), nonhuman tissue (xenographic), synthetic materials, or a composite of these materials. Bioengineered skin and soft tissue substitutes are being evaluated for a variety of conditions, including breast reconstruction and healing lower-extremity ulcers and severe burns. Acellular dermal matrix (ADM) products are also being evaluated for soft tissue repair.

10. Organ Engineering

This interdisciplinary engineering has attracted much attention as a new therapeutic means that may overcome the drawbacks involved in the current artificial organs and organ transplantation that have been also aiming at replacing lost or severely damaged tissues or organs. Tissue engineering and regenerative medicine is an exciting research area that aims at regenerative alternatives to harvested tissues for organ transplantation with soft tissues. Although significant progress has been made in the tissue engineering field, many challenges remain and further development in this area will require on-going interactions and collaborations among the scientists from multiple disciplines, and in partnership with the regulatory and the funding agencies. As a result of the medical and market potential, there is significant academic and corporate interest in this technology.

11. Stem Cell Therapy

Stem cell therapy is the use of stem cells to treat or prevent a disease or condition. Bone marrow transplant is the most widely used stem-cell therapy, but some therapies derived from umbilical cord blood are also in use. Research is underway to develop various sources for stem cells, and to apply stem cell treatments for neurodegenerative diseases and conditions such as diabetes, heart disease, and other conditions. Stem cell therapy has become controversial following developments such as the ability of scientists to isolate and culture embryonic stem cells, to create stem cells using somatic cell nuclear transfer and their use of techniques to create induced pluripotent stem cells. This controversy is often related to abortion politics and to human cloning.

Additionally, efforts to market treatments based on transplant of stored umbilical cord blood have been controversial.

12. Trends in Tissue Engineering

There are more than 200 types of cancer, including Breast cancer, skin cancer, lung cancer, colon cancer, Prostate cancer, and lymphoma. Symptoms and Treatment varies depending on the type of Cancer. Some people with cancer will have only one treatment. But most people have a combination of treatments, such as surgery with chemotherapy and/or radiation therapy. The Anticancer therapies include surgical therapy, Chemotherapy, Adjuvant therapy, Neoadjuvant therapy, Palliative therapy, Immunotherapy, Hormonal therapy, Radiotherapy, Nutritional therapy, Phototherapy. Phototherapy / proton beam therapy is the most advanced among all the therapies. All Anticancer agents act by disturbing cell multiplication or normal functioning, DNA synthesis or chromosomal migration, and by blocking or changing RNA and protein metabolism.

13. Cancer Therapy

Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. Not all tumours are cancerous; benign Tumours do not spread to other parts of the body. Possible signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in bowel movements. While these symptoms may indicate cancer, they may have other causes. Over 100 types of cancers affect humans.

14. Bone Tissue Engineering

Tissue engineering of musculoskeletal tissues, particularly bone and cartilage, is a rapidly advancing field. In bone, technology has centred on bone graft substitute materials and the development of biodegradable scaffolds. Recently, tissue engineering strategies have included cell and gene therapy. The availability of growth factors and the expanding knowledge base concerning the bone regeneration with modern techniques like recombinant signalling molecules, solid free form fabrication of scaffolds, synthetic cartilage, Electrochemical deposition, spinal fusion and ossification are new generated techniques for tissue-engineering applications. The worldwide market for bone cartilage repairs strategies is estimated about $300 million. During the last 10/15 years, the scientific community witnessed and reported the appearance of several sources of stem cells with both osteon and chondrogenic potential.

15. Cell Culture & Bio Reactors

Bioreactors come in a variety of sizes, shapes, and forms. Single-use bioreactors for cell culture were introduced to the market in the mid-90s and they are now widely used in process development, research, and manufacturing up to 2000 L scale. Disposable technology brings an increased speed and flexibility to bioprocessing and decreases cleaning validation costs.

16. Patient Specific Drug Discovery

In vitro cell models are invaluable tools for studying diseases and discovering drugs. Human induced pluripotent stem cells, particularly derived from patients, are an advantageous resource for generating ample supplies of cells to create unique platforms that model disease. This manuscript will review recent developments in modeling a variety of diseases (including their cellular phenotypes) with induced pluripotent stem cells derived from patients. It will also describe how researchers have exploited these models to validate drugs as potential therapeutics for these devastating diseases.

17. Cell & Gene Therapy

Gene therapy aims to transfer genetic material into cells to provide them with new functions. A gene transfer agent has to be safe, capable of expressing the desired gene for a sustained period of time in a sufficiently large population of cells to produce a biological effect. Identifying a gene transfer tool that meets all of these criteria has proven to be a difficult objective. Viral and no viral vectors, in vivo, ex vivo and in situ strategies co-exist at present, although ex vivo lenti-or retroviral vectors are presently the most popular. Natural stem cells (from embryonic, hematopoietic, mesenchymal, or adult tissues) or induced progenitor stem (iPS) cells can be modified by gene therapy for use in regenerative medicine.

18. Embryonic Stem Cell

Embryonic stem cells are pluripotent, meaning they are able to grow (i.e. differentiate) into all derivatives of the three primary germ layers: ectoderm, endoderm and mesoderm. In other words, they can develop into each of the more than 200 cell types of the adult body as long as they are specified to do so. Embryonic stem cells are distinguished by two distinctive properties: their pluripotency, and their ability to replicate indefinitely. ES cells are pluripotent, that is, they are able to differentiate into all derivatives of the three primary germ layers: ectoderm, endoderm, and mesoderm. These include each of the more than 220 cell types in the adult body. Pluripotency distinguishes embryonic stem cells from adult stem cells found in adults; while embryonic stem cells can generate all cell types in the body, adult stem cells are multipotent and can produce only a limited number of cell types. Additionally, under defined conditions, embryonic stem cells are capable of propagating themselves indefinitely. This allows embryonic stem cells to be employed as useful tools for both research and regenerative medicine, because they can produce limitless numbers of themselves for continued research or clinical use.

19. Bone and Cartilage Tissue Engineering

The tremendous need for bone tissue in numerous clinical situations and the limited availability of suitable bone grafts are driving the development of tissue engineering approaches to bone repair. In order to engineer viable bone grafts, one needs to understand the mechanisms of native bone development and fracture healing, as these processes should ideally guide the selection of optimal conditions for tissue culture and implantation. Engineered bone grafts have been shown to have capacity for Osteogenesis, osteoconduction, osteoinduction and osteointegration - functional connection between the host bone and the graft. Cells from various anatomical sources in conjunction with scaffolds and osteogenic factors have been shown to form bone tissue in vitro. The use of bioreactor systems to culture cells on scaffolds before implantation further improved the quality of the resulting bone grafts. Animal studies confirmed the capability of engineered grafts to form bone and integrate with the host tissues. 

20. Scaffolds for Tissue Engineering

Tissue engineering along with regenerative medicine can be used to create ‘Scaffolds’ in the human body. These scaffolds are used to support organs and organ systems that may have been damaged after injury or disease. So what is tissue engineering? ‘Tissue engineering is the use of a combination of cells, engineering and materials methods, and suitable biochemical and physico-chemical factors to improve or replace biological functions’. This is most commonly achieved through the use of stem cells. Stem cells are unique types of cells that are undifferentiated. So the main focus of creating these constructs is to be able to safely deliver these stem cells, and create a structure that is physically and mechanically stable so that these stem cells can differentiate. Scaffolds are of great importance in clinical medicine. It is an upcoming field, and usually associated with conditions involving organ disease or failure. It is used to rebuild organs and return normal function.

Related Conferences

Drug delivery and tissue engineering conference 2018, February 4-8, 2018, Singapore; 20th International conference on Tissue engineering and Biomaterials, Feb 19-20, 2018, Paris; Global Summit on Stem Cell & Tissue Engineering 2018, July 23-24, 2018 Barcelona, Spain.19th International Conference on Tissue Engineering and RegenerativeMedicine Applications, September21-22, Paris, France;12th International conference on Tissue Engineering and Regenerative Medicine, November 09-10, Atlanta;3rd world Congress on Human Genetics & Genetic Disorders, October 20-21,2017,Canada; 12th International conference on Tissue Preservation & Biobanking, November 09-10, Atlanta;7th Annual Congress & Medical Expo on Primary Health Care and Nursing 2018,June 25-26,Canada.

                                                                                                                   

 

Market Analysis

USA: Regenerative medicines market by therapy (cell therapy, gene therapy, immunotherapy, tissue engineering), region - global forecast to 2021, the global regenerative medicines market size is expected to reach USD 49.41 billion by 2021,. North America contributed the largest share in the global regenerative medicines market, and was dominated largely by the USA
 

Europe: The global tissue engineering and regeneration market reached $17 billion in 2016. This market is expected to grow to nearly $20.8 billion in 2014 and $56.9 billion in 2019, Today, there are 640 privately held and publicly traded companies in Europe, Japan, and the U.S.

 

Middle East: Middle East and Africa regenerative medicines market is expected to reach USD 5.75 billion by 2021 from USD 2.03 billion in 2018, growing at a CAGR of 23.15% during the forecast period 2016-2021. Regenerative medicines repair, replace or regenerate human cells, tissues, or organs affected due to injury, disease, aging processes, congenital defects, and damage due to trauma.

 

Asia Pacific: Asia-Pacific regenerative medicines market is expected to reach USD 10.71 billion by 2021 from USD 3.01 billion in 2017, growing at a CAGR of 28.90% during the forecast period 2017-2021.  Cell-based products segment is estimated to account for larger share of Asia-Pacific regenerative medicines market by product in 2018.

 

 

 

Past Conference Report

Tissue Science 2017

Tissue Science 2017 Report

6th International Conference on Tissue Engineering and Regenerative Medicine was organized during August 23-24, 2017 at San Francisco, USA. The conference was marked with the attendance of Editorial Board Members of supporting journals, Scientists, young and brilliant researchers, business delegates and talented student communities representing more than 25 countries, who made this conference fruitful and productive.

This conference was based on the theme “Importance of Tissue Engineering and Regenerative Medicine to the Future of Health Care” which included the following scientific tracks:

  • Tissue Regeneration using Nanotechnology
  • Tissue Repair and Regeneration
  • Biological Tissue Substitutes
  • Organ Engineering
  • Trends in Tissue Engineering
  • Bone Tissue Engineering
  • Cell Culture & Bio Reactors
  • Patient Specific Drug Discovery
  • Tooth Regeneration
  • Regenerative medicine
  • Applications of Tissue Engineering
  • Regenerative Medicine Market
  • Embryonic Stem Cell
  • Stem Cell Transplant

The Organizing Committee would like to thank the moderator Dr. Joel I Osorio (University of Californian Los Angeles, USA) and Dr. Seungil Ro for their contribution which resulted in smooth functioning of the conference.

The conference proceeded through various scientific sessions and plenary lectures, of which the following topics were highlighted as Keynote presentations:

Panayiotis Zavos -The Evolution and Current Status of Sperm Cryopreservation (The Andrology Institute of America, USA)

Heiko Zimmerman- Improved methods and procedures for pluripotent stem cell preservation, storage stability and validation (Fraunhofer Institute for Biomedical Engineering, Germany)

Aubrey de Grey- Cryopreservation of organs and organisms: Signs of a new era  (SENS Research Foundation, USA)

Igor Katkov- Cryopreservation by Vitrification: Basic Thermodynamic Principals, Methods and Devices (Belgorod National Research University, Russia)

Ken Yaegaki- Transplantation of hepatocyte like cells derived from human tooth into the animals with liver conditions (Nippon Dental University School of Life Dentistry, Japan)

Charles F Mahl- Prolotherapy – The first choice in Regenerative Medicine (GenLife Institute for Regenerative Medicine and Stem Cells, USA)

Luiz C. Samapio - Maximizing Cardiac Repair: Should We Focus on Cells or Matrix?( Texas Heart Institute, USA)

Various sessions were chaired and co-chaired by: Panayiotis Zavos, The Andrology Institute of America, USA; Heiko Zimmerman, Fraunhofer Institute for Biomedical Engineering, Germany and
Debra Aub Webster, Cardinal Health Regulatory Sciences, USA; Ken Yaegaki, Nippon Dental University School of Life Dentistry, Japan

 Conferenceseries LLC has taken the privilege of felicitating Tissue Science 2017 Organizing Committee, Editorial Board Members and Keynote Speakers who supported for the success of this conference.

The esteemed guests, keynote speakers and researchers shared their innovative research and vast experience through their informative presentations at the podium of Tissue Science 2017. We are glad to inform that all accepted abstracts for the conference have been published in Journal of Tissue Science & engineering: Open Access as a special issue.

We are also obliged to various experts, company representatives and other eminent scientists who supported the conference by facilitating the discussion forums. We sincerely thank the Organizing Committee Members for their gracious presence, support, and assistance. With the unique feedback from the conference, Conferenceseries LLC would like to proudly announce the commencement of the “12th International Conference on Tissue Engineering and Regenerative Medicine “to be organized during November 09-10, 2018 at Atlanta, USA.

Mark your calendars for the upcoming Conference; we are hoping to see you soon!

For More details: http://tissuescience.conferenceseries.com/


Past Reports  Proceedings  Gallery  

To Collaborate Scientific Professionals around the World

Conference Date November 9-10 , 2018

For Sponsors & Exhibitors

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Journal of Tissue Science & Engineering Journal of Biomimetics Biomaterials and Tissue Engineering Journal of Cell Science & Therapy

All accepted abstracts will be published in respective Conferenceseries International Journals.

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